Van Dessel E et al. Ventilatory efficiency is improved during flow-controlled ventilation in ARDS. Intensive Care Medicine Experimental 2020, 9(1):001167.
This study represents the first prospective crossover trial in 11 patients with moderate ARDS from Covid-19, with the aim to compare the ventilatory efficiency of FCV to VCV. Patients received a ventilation sequence of PCV (baseline), followed by 30 minutes FCV and VCV. Ventilation settings were aimed to be kept comparable between the ventilation modes. With similar arterial CO2 values, the applied minute volume was significantly (16%) lower in FCV compared to VCV (6.6 L/min vs VCV 7.9 L/min; P<0.001), indicating a higher ventilation efficiency with FCV
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