Berlin et al. Automated expiratory ventilation assistance through a small endotracheal tube can improve venous return and cardiac output. Intensive Care Med Exp. 2019
Prof Heerdt and co-workers showed in a porcine model that EVA ventilation with a Negative End Expiratory Pressure (NEEP; -8 mbar) improved hemodynamics during noromvolemia and during hypovolemia after hemorrhage as compared with VCV with PEEP. Before hemorrhage EVA-NEEP increased stroke volume (+27%; p=0.003) and cardiac output (+21%; p=0.023), and reduced central venous pressure (-30%; p=0.013) compared with Volume Controlled Ventilation with PEEP (4 mbar). After hemorrhage during hypovolemia the effects were more pronounced leading to an 41% increased cardiac output, higher mean arterial pressure and increased venous return for EVA -NEEP ventilation as compared with VCV-ZEEP (0 mbar). For this study a prototypical small automated ventilator based upon the EVA principle was used to generate a controlled period of negative EEP.
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Our journey to redefine ventilation continues. Tuesday evening Prof. Dr. med. Dietmar Enk spoke at the Spring Symposium in Gent, Belgium. Topics were ventilation method FCV® and energy minimalization. During day time, there were various clinical demonstrations....