Literature

Clinical use, pre-clinical validation and technology development of our products have been published. Ventinova’s products are also included in various handbooks. Relevant references can be found on this page.

Or you can download our Literature List:

Literature List

Abram et al. Improved ventilation efficiency due to continuous gas flow compared to decelerating gas flow in mechanical ventilation – results of a porcine trial. Am J Physiol Lung Cell Mol Physiol 2023

Evone, Higher Efficiency, Lower Energy

Abram et al. Individualised flow-controlled versus pressure-controlled ventilation in a porcine oleic acid-induced acute respiratory distress syndrome model. Eur J Anaesth 2023

Evone, Higher Efficiency, Lower Energy

Schranc et al. Flow-controlled ventilation maintains gas exchange and lung aeration in a pediatric model of healthy and injured lungs: A randomized cross-over experimental study. Front Pediatr. 2022

Evone, Higher Efficiency, Lower Energy

Spraider et al. Individualised flow-controlled ventilation versus pressure-controlled ventilation in a porcine model of thoracic surgery requiring one-lung ventilation: A laboratory study. Eur J Anaesthesiol 2022; 37:1 – 10

Evone, Higher Efficiency, Lower Energy

Grassetto et al. A new perspective during laryngo-tracheal surgery: the use of an ultra-thin endotracheal tube (Tritube®) and flow-controlled ventilation—a retrospective case series and a review of the literature. J Anesth Analg Crit Care 2022

Evone, Small Lumen, Tritube, Upper Airway Surgery

Kuut et al. Controlled mechanical ventilation through a narrow bore lumen during tracheal surgery. Eur J Anaesthesiol. 2022

Evone, Small Lumen, Tritube, Upper Airway Surgery

Grassetto et al. Flow-controlled ventilation may reduce mechanical power and increase ventilatory efficiency in severe coronavirus disease-19 acute respiratory distress syndrome. Pulmonology 2022

Evone, Higher Efficiency, Lower Energy

Filauro et al. Evone® Flow controlled ventilation: a new device for laryngotracheal surgery. Acta Otorhinolaryngol Ital. 2022

Evone, Small Lumen, Tritube, Upper Airway Surgery

Nouraei et al. A multidisciplinary approach for managing the infraglottic difficult airway in the setting of the Coronavirus pandemic. Oper Tech Otolaryngol Head Neck Surg. 2020

Cricath, Evone, Small Lumen, Tritube, Upper Airway Surgery, Ventrain

Silva et al. Personalized Mechanical Ventilation Settings: Slower Is Better! In: Annual Update in Intensive Care and Emergency Medicine 2022

Evone, Higher Efficiency, Lower Energy

Mallam et al. & Response by Böttinger et al. Near total intrathoracic airway obstruction managed with a Tritube® and flow-controlled ventilation. Anaesthesia Reports 2022

Evone, Small Lumen, Tritube, Upper Airway Surgery

Leow et al. Intubation with a TriTube to avoid peri-operative tracheostomy in open airway surgery. The Journal of Laryngology & Otology 2022

Evone, Small Lumen, Tritube, Upper Airway Surgery

Bialka et al. Flow-controlled ventilation – a new and promising method of ventilation presented with a review of the literature. Anaesthesiol Intensive Ther 2022; 54, 1: 1–9

Evone, Higher Efficiency, Small Lumen, Tritube, Upper Airway Surgery

De Wolf et al. Ventilation through small-bore airways in children by implementing active expiration. Pediatric Anesthesia. 2022;32:312–320.

Emergency, Small Lumen, Ventrain

Dos Santos Rocha et al. Novel ventilation techniques in children. Paediatr Anaesth. 2021 Nov 27. doi: 10.1111/pan.14344. Epub ahead of print. PMID: 34837438.

Emergency, Evone, Small Lumen, Ventrain

Van Dessel et al. Flow-controlled ventilation in moderate acute respiratory distress syndrome due to COVID-19: an open-label repeated-measures controlled trial. Intens Care Med Exp. 2022

Evone, Higher Efficiency

Piccioni F et al. Use of the Ventrain Ventilation Device and an Airway Exchange Catheter to Manage Hypoxemia During Thoracic Surgery and One-Lung Ventilation. J Cardiothorac Vasc Anesth. 2021 Jun 25:S1053-0770(21)00529-2. doi: 10.1053/j.jvca.2021.06.023. Epub ahead of print. PMID: 34294514.

Small Lumen, Ventilation during Lung Separation Procedures, Ventrain

Yilbas AA et al. Experience with Tritube and Flow-Controlled Ventilation During Airway Surgery. Turk J Anaesthesiol Reanim. 2021;49(3):269-270.

Evone, Small Lumen, Tritube, Upper Airway Surgery

Bailey JR et al. Laryngectomy with a Tritube® and flow-controlled ventilation. Anaesth Rep. 2021 May 7;9(1):86-89. doi: 10.1002/anr3.12114.

Evone, Small Lumen, Tritube, Upper Airway Surgery

Spraider P et al. A case report of individualized ventilation in a COVID-19 patient – new possibilities and caveats to consider with flow-controlled ventilation. BMC Anesthesiol. 2021 May 12;21(1):145.

Evone, Higher Efficiency, Lower Energy

Shallik N et al. Management of critical tracheal stenosis with a straw sized tube (Tritube): Case report. Qatar Med J. 2021 Jan 28;2020(3):48. doi: 10.5339/qmj.2020.48.

Evone, Small Lumen, Tritube, Upper Airway Surgery

Ordies S et al. Flow-controlled ventilation during EVLP improves oxygenation and preserves alveolar recruitment. Intensive Care Med Exp. 2020 Nov 25;8(1):70. doi: 10.1186/s40635-020-00360-w.

Evone, Lower Energy

Wittenstein J et al. Comparative effects of flow vs. volume-controlled one-lung ventilation on gas exchange and respiratory system mechanics in pigs. Intensive Care Med Exp. 2020 Dec 18;8(Suppl 1):24. doi: 10.1186/s40635-020-00308-0

Evone, Higher Efficiency, Lower Energy

Schleicher A and Groeben H. Anesthetic considerations for tracheobronchial surgery. J Thorac Dis. 2020 Oct;12(10):6138-6142. doi: 10.21037/jtd.2020.02.52.

Evone, Small Lumen, Tritube, Upper Airway Surgery

Mann CM et al. A comparison of cannula insufflation device performance for emergency front of neck airway. Paediatr Anaesth. 2021 Jan 11. doi: 10.1111/pan.14128. Epub ahead of print. PMID: 33432628.

Emergency, Ventrain

Sebrechts T et al. Flow-controlled ventilation with the Evone ventilator and Tritube versus volume-controlled ventilation. Eur J Anaesthesiol. 2021 Feb 1;38(2):209-211. doi: 10.1097/EJA.0000000000001326

Evone, Higher Efficiency

Magasich-Airola NP et al. Novel technique for safe tracheostomy during COVID-19 pandemic using Evone® flow-controlled ventilation system. Int J Clin Pract. 2020 Nov 27;e13863. doi: 10.1111/ijcp.13863. Online ahead of print.

Evone, Small Lumen, Tritube, Upper Airway Surgery

Spraider P et al. Individualized flow-controlled ventilation compared to best clinical practice pressure controlled ventilation: a prospective randomized porcine study. Int J Crit Care 2020 Nov 25;24(1):662. doi: 10.1186/s13054-020-03325-3.

Evone, Higher Efficiency

Meulemans et al. Evone® Flow-Controlled Ventilation During Upper Airway Surgery: A Clinical Feasibility Study and Safety Assessment. Front. Surg. 2020; 7:6.

Evone, Higher Efficiency, Small Lumen, Tritube, Upper Airway Surgery

Weber et al. Flow-controlled ventilation (FCV) improves regional ventilation in obese patients – a randomized controlled crossover trial. BMC Anesthesiol 2020;20(1):24

Evone, Higher Efficiency, Lower Energy

Schmidt et al. Flow-Controlled Ventilation Attenuates Lung Injury in a Porcine Model of Acute Respiratory Distress Syndrome: A Preclinical Randomized Controlled Study. Crit Care Med. 2020 Mar;48(3):e241-e248

Evone, Higher Efficiency, Lower Energy

Weber et al. Flow-controlled ventilation improves gas exchange in lung-healthy patients – a randomised interventional cross-over study. Acta Anaesthesiol Scand. 2019 Dec 12. doi: 10.1111/aas.13526. [Epub]

Evone, Higher Efficiency

Bergold et al. Flow-controlled ventilation – a novel approach to treating severe acute respiratory distress syndrome. Poster presented at WAMM 2019.

Evone, Higher Efficiency, Lower Energy

Lee et al. The Ventrain: An elegant way to facilitate elective surgery in upper airway obstruction. Trends in Anaesthesia and Critical Care 2020 (30) e13

Cricath, Upper Airway Surgery, Ventrain

Schmidt et al. Glottic visibility for laryngeal surgery: Tritube® vs. microlaryngeal tube – a randomized controlled trial. Eur J Anaesthesiol. 2019; 36:963-971

Evone, Higher Efficiency, Small Lumen, Tritube, Upper Airway Surgery

Spraider et al. Improved ventilation and lung recruitment in flow-controlled ventilation (FCV) compared to pressure-controlled ventilation (PCV) – A prospective, randomized porcine study. Abstract presented at ESICM 2019 and AIC 2019.

Evone, Higher Efficiency, Lower Energy

Morrison et al. The Ventrain Device: A Future Role in Difficult Airway Algorithms? A&A Practice. 2019;13:362-365

Emergency, Small Lumen, Upper Airway Surgery, Ventrain

Piosik et al. Ultra-narrow 2.4 mm id Tritube® together with Evone® ventilation allows surgical access and controlled ventilation even in case of severe stenosis. Trends in Anaesthesia and Critical Care 2018 (23); 20

Evone, Small Lumen, Tritube, Upper Airway Surgery

Rodríguez et al. Cutting-edge ventilation method in laryngeal microsurgery. Abstract #3280 presented at Euroanaesthesia 2019

Small Lumen, Tritube

Kristensen et al. Endotracheal video-laryngoscope guided intubation with a 2.4 mm cuff’ed tube and active expiration by a dedicated ventilator versus a standard tube/ventilator. A randomized single blinded study in patients with a predicted difficult airway. – A paradigm shift in airway management? Abstract #3755 presented at Euroanaesthesia 2019 – Manuscript in preparation

Evone, Small Lumen, Tritube

Zuercher et al. Combined use of Ventrain and S-Guide for Airway Management of Severe Subglottic Stenosis. Turk J Anaesthesiol Reanim. 2019;47(3):238-241. doi:10.5152/TJAR.2019.75428

Small Lumen, Ventrain

Böttinger and Van der Hoorn. Negative pressure ventilation – a special application of expiratory ventilation assistance. Intensive Care Med Exp 2019, 7(1), 22

Technology Development

Schmidt et al. Flow-controlled ventilation during ear, nose and throat surgery. A prospective observational study. Eur J Anaesthesiol. 2019

Evone, Small Lumen, Tritube

Morrison et al. Failed Awake Intubation for Critical Airway Obstruction Rescued With the Ventrain Device and an Arndt Exchange Catheter: A Case Report. A A Pract. 2019 Feb 5 (Epub ahead of print)

Ventrain

Berlin et al. Automated expiratory ventilation assistance through a small endotracheal tube can improve venous return and cardiac output. Intensive Care Med Exp. 2019, 7(1), 6

Technology Development

Barnes and Enk. Ventilation for low dissipated energy achieved using flow control during both inspiration and expiration. Trends in Anaesthesia and Critical Care 24 (2019); 5-12

Evone, Lower Energy

Barnes et al. Minimisation of dissipated energy in the airways during mechanical ventilation by using constant inspiratory and expiratory flows-Flow controlled ventilation (FCV). Medical Hypotheses 121 (2018); 167-176

Evone, Lower Energy

Doyle. Ventilation via Narrow-Bore Catheters: Clinical and Technical Perspectives on the Ventrain Ventilation System. The Open Anaesthesia Journal Sep 2018; 12, 49-60

Cricath, Emergency, Higher Efficiency, Small Lumen, Ventrain

Jeyarajah and Ahmad. Awake tracheal placement of the Tritube® under flexible bronchoscopic guidance. Anaesthesia Cases / 2018-0097 / ISSN 2396-8397 epub Jul 2018

Evone, Small Lumen, Tritube, Upper Airway Surgery

Heuveling et al. Transtracheal Use of the CriCath Cannula in Combination With the Ventrain Device for Prevention of Hypoxic Arrest due to Severe Upper Airway Obstruction: A Case Report. A A Pract. 2018 Dec 15;11(12):344-347

Cricath, Emergency, Small Lumen, Ventrain

Schmidt et al. Improved lung recruitment and oxygenation during mandatory ventilation with a new expiratory ventilation assistance device: Eur J Anaesthesiol. 2018 Oct;35(10):736-744

Evone, Higher Efficiency

Escribá et al. Emergency Ventilation of Infant Subglottic Stenosis Through Small-Gauge Lumen Using the Ventrain: A Case Report. A A Prac 2018 Mar 15;10(6):136-138

Emergency, Small Lumen, Ventrain

Kristensen et al. Ventilation via the 2.4 mm internal diameter Tritube® with cuff – new possibilities in airway management. Acta Anesthesiol. Scand. 2017 Jul; 61(6):580-589

Small Lumen, Upper Airway Surgery, Ventrain

De Wolf et al. Emergency ventilation with the Ventrain_through an airway exchange catheter in a porcine model of complete upper airway obstruction. Can J Anaesth. 2017 Jan;64(1):37-44

Emergency, Small Lumen, Ventrain

Schmidt et al. Monitoring in- and expiratory tidal volumes in the new Ventrain® emergency ventilation device. Poster Airway management symposium 2013

Small Lumen, Technology Development, Ventrain

Enk et al. Small Lumen Ventilation through a Cuffed Jet Ventilation Catheter: Efficiency and Safety. Poster Airway Management 2012

Small Lumen, Technology Development, Ventrain

Dias et al. Adequate minute volume ventilation through a 100 cm long, 3 mm inner diameter airway exchange catheter by expiratory ventilation assistance (EVA). Poster ESA 2012

Small Lumen, Technology Development, Ventrain

Calderon et al. Expiratory ventilation assistance (EVA) through a 14G catheter (2mm) in a Totally Obstructed Airway (TOA). Poster SAM 2013

Small Lumen, Technology Development, Ventrain

Hamaekers et al. A bench study of ventilation via two self-assembled jet devices and the Oxygen Flow Modulator in simulated upper airway obstruction. Anaesthesia. 2009 Dec;64(12):1353-8

Small Lumen, Technology Development, Ventrain

Hamaekers et al. The importance of flow and pressure release in emergency jet ventilation devices. Paediatr Anaesth. 2009 May;19(5):452-7

Small Lumen, Technology Development, Ventrain

Hamaekers et al. Achieving an adequate minute volume through a 2 mm transtracheal catheter in simulated upper airway obstruction using a modified industrial ejector. Br J Anaesth. 2010

Small Lumen, Technology Development, Ventrain

Hamaekers et al. Ventilation through a small-bore catheter: optimizing expiratory ventilation assistance. Br J Anaesth. 2011

Small Lumen, Technology Development, Ventrain

Hamaekers, et al. Ventrain: an ejector ventilator for emergency use. Br J Anaesth. 2012 Jun; 108 (6): 1017-21

Small Lumen, Technology Development, Ventrain

Manoach et al. Resuscitation from prolonged apnea and upper airway obstruction in a large ovine model: a pilot trial of transtracheal ventilation using 15 lpm with and without an entrainment assisted trans-catheter exhalation device. Poster SAM 2011

Emergency, Small Lumen, Ventrain

Ziebart et al. Pulmonary effects of expiratory-assisted small-lumen ventilation during upper airway obstruction in pigs. Anaesthesia. 2015

Emergency, Small Lumen, Ventrain

Berry et al. Percutaneous transtracheal ventilation in an obstructed airway model in post apnoeic sheep. Br J Anaesth. 2014

Emergency, Higher Efficiency, Small Lumen, Ventrain

Hamaekers et al. Rescue ventilation through a small-bore transtracheal cannula in severe hypoxic pigs using expiratory ventilation assistance. Anesth Analg. 2015 Apr; 120 (4):890-4

Emergency, Small Lumen, Ventrain

Paxian et al. Transtracheal ventilation with a novel ejector-based device (Ventrain) in open, partly obstructed, or totally closed upper airways in pigs. Br J Anaesth 2015

Emergency, Higher Efficiency, Small Lumen, Ventrain

Kalsi et al. Transtracheal jet ventilation using the Ventrain Device in a patient with severe upper airway obstruction. Poster DAS 2012

Emergency, Small Lumen, Ventrain

Nellgård. Ventrain in a case of can´t intubate can´t ventilate situation. Abstract ESA 2013

Emergency, Small Lumen, Ventrain

Krapf et al. Cannot intubate, cannot ventilate: Beatmung über einen 2-mm-Katheter in der Präklinik. Notfallpraxis 2016 8(39); 792-794 (article in German)

Emergency, Small Lumen, Ventrain

López-Torres et al. Ventrain device for difficult or obstructed airway: 4 case report. Abstracts / Trends in Anesthesia and Critical Care 2017; 12:31

Emergency, Small Lumen, Ventrain

Willemsen et al. Ventilation with the Ventrain through a small lumen catheter in the failed paediatric airway: two case reports. Br J Anaest 2014

Emergency, Small Lumen, Ventrain

Wahlen et al. Ventrain: from theory to practice. Bridging until re-tracheostomy BJM Case Rep 2017

Emergency, Small Lumen, Ventrain

Escribá Alepuz et al. Emergency Ventilation of Infant Subglottic Stenosis Through Small-Gauge Lumen Using the Ventrain: A Case Report. A&A Case Reports. Oct 24 2017

Emergency, Small Lumen, Ventrain

Evers et al. Intraoperative Use of the Ventrain for Single Lung Ventilation After Iatrogenic Trauma to the Left Main Bronchus During Thoracoscopy: A Case Report. AA Case Rep 2017 Aug 15; 9 (4): 116-118

Ventilation during Lung Separation Procedures, Ventrain

Van der Beek et al. Optimizing ventilation through a cuffed narrow bore catheter (CNBC) using expiratory ventilation assistance (EVA): an animal study. Poster ESA 2013

Small Lumen, Ventrain

Paxian et al. Transtracheal ventilation with a novel ejector-based device (Ventrain) in open, partly obstructed, or totally closed upper airways in pigs. Br J Anaesth 2015

Small Lumen, Ventrain

De Wolf et al. A prototype small-bore ventilation catheter with a cuff: cuff inflation optimizes ventilation with the Ventrain. Acta Anaesth Scand 2017

Small Lumen, Tritube, Ventrain

Braga et al. Ventrain ejector ventilation as a bridge to tracheal intubation for complex MOMA pathology – Poster WAMM 2015

Small Lumen, Upper Airway Surgery, Ventrain

Kalkoff. Ventilation through a small-bore intubating catheter using Ventrain in an elective procedure. Letter Br J Anaesth 2012

Small Lumen, Upper Airway Surgery, Ventrain

Monnier et al. Transthyrohyoid access to the larynx for endoscopic resection of early-stage glottic cancer. Head Neck 2016 Apr

Small Lumen, Upper Airway Surgery, Ventrain

Borg et al. Ventrain for ventilation of the lungs. Br J Anaesth. 2012 Nov

Small Lumen, Upper Airway Surgery, Ventrain

Fearnley et al. Elective use of the Ventrain for upper airway obstruction during high frequency jet ventilation. J Clin Case Rep 2016

Cricath, Small Lumen, Upper Airway Surgery, Ventrain

Onwochei et al. Two-Stage Technique Used to Manage Severe Upper Airway Obstruction and Avoid Surgical Tracheostomy: A Case Report. A&A Case Rep 2017

Cricath, Small Lumen, Upper Airway Surgery, Ventrain

Rosenblatt and Popescu. Master techniques in Upper and Lower Airway Management. Wolters Kluwer Health (publisher); 2015

Small Lumen, Ventrain

Dornberger. Schwieriges Atemwegsmanagement bei Erwachsenen und Kindern. Thieme (publisher); 2013

Small Lumen, Ventrain

Spies et al. SOPs in Anästesiologie und Schmerztherapie. Thieme (publisher); 2013

Small Lumen, Ventrain

Barash et al. Clinical Anesthesia, 7th ed., Wolters Kluwer Health (publisher); 2013

Small Lumen, Ventrain

Hagberg, Benumof & Hagberg’s Airway Management, 3th ed. Elsevier (publisher); 2013

Cricath, Small Lumen, Ventrain

Hagberg, Benumof & Hagberg’s Airway Management, 4th ed. Elsevier (publisher); 2018

Cricath, Small Lumen, Ventrain

Timmermann et al. Need to consider human factors when determining first-line technique foremergency front-of-neck access. Br J Anaesth. 2016 May 20

Cricath, Emergency, Small Lumen, Ventrain

Noppens. Ventilation through a ‘straw’: the final answer in a totally closed upper airway? Br J Anaesth. 2015

Small Lumen, Upper Airway Surgery, Ventrain

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Symposium organized by Erasmus Medical Center

Sep 26, 2022

Erasmus Medical Center (Rotterdam, the Netherlands) is organizing a hybrid symposium on Flow Controlled Ventilation blowing away VILI.The event will be held on the 28th of October in Rotterdam but can also be watched online.For more information click...

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